Interphex 2018

 

We are proud to announce the presence of our manufacturers to this years Interphex Expo that’s taking place this week at the Javits Center in New York City.

INTERPHEX has proven to be the place to find all of the State-of-the-Art Solutions you need to Cost Effectively Develop and Manufacture Quality Product. INTERPHEX is the premier pharmaceutical, biotechnology, and device development and manufacturing event where you can “Experience Science through Commercialization”

 

If you are planning on attending this tradeshow please take note of our manufacturers Booths and the equipment that they will be exhibiting on the show.

 

Bahnson Environmental Specialties, LLC. – Raleigh, NC
Presenting their complete line of Walk-In and Reach-In Controlled Environmental Chambers designed for diverse pharmaceutical applications including HEPA Filtered Cold Rooms, modular and traditional Clean Rooms, Stability Chambers exceeding ICH guidelines and high capacity -75°C Cascade low temperature storage chambers. BES will present information on 3  of their unique High Volume Freezer designs for the biorepository storage market that allow reduced dependence on small unitary freezers.

Come see Bahnson at Booth: 1945

 

LF of America, the US subsidiary of Lameplast group is going to exhibit at INTERPHEX 2018!

Lameplast Group is a worldwide leading manufacturer of plastic containers for the pharmaceutical and personal care industries. With more than 35 years of experience and a US branch located in Florida, the companies of Lameplast Group offer true turn-key solutions including the supplying of fully-automated semi-automated filling and sealing machines.

See their machinery and get some packaging samples at their BOOTH: 2364

Cozzoli Machine Company will be exhibiting at INTERPHEX 2018.

As a single source provider for individual components to fully integrated lines, they offer production solutions for every application, from pharmaceutical, cosmetic, e-liquid, health, beauty aids, personal care, food and beverage, chemical, paint and industrial products. Featured machines include the RPF8 Rotary Piston Filler, the FSV50 Mini Monoblock, the GW24 Ampule/Vial Batch Washer, and the PF2-IS powder filler. Cozzoli will also be showing their tabletop F400XSS Liquid Filler.

Stop by to see our latest technology in Booth 2805

To set up a booth meeting, please contact Cozzoli at (732) 564-0400 or sales@cozzoli.com. We look forward to seeing you at the show!

Claim a free pass for the exhibition HERE!

 

Fedegari Announces the Next Sterilization and Aseptic Processing Week.

 

There is no doubt that for achieving the highest performances with our sterilizers you need to fully understand the process also from a scientific standpoint. This is the reason why we have Fedegari teaming up with Jim Agalloco in order to offer you the most effective education.

 

This year, we are glad to inform you that Jim will hold two different courses in Zurich (Switzerland), covering all the subjects relevant to sterilization and beyond, as following:

 

STERILIZATION: PRINCIPLES AND VALIDATION

ASEPTIC PROCESSING: A COMPREHENSIVE REVIEW

Take Either Course or Save on Both

MAY 28 – JUNE 1, 2018, ZURICH, SWITZERLAND

 

The tentative schedule for the course can be found on this location: http://www.fedegari.com/en/agalloco-associates-2018-training-offerings/

 

If a Euro trip is out of the picture for your facility, please get in touch with our representatives and we’ll make sure to host several training sessions on US soil.

 

Don’t miss the opportunity to join us at these classes and book your place by clicking here!

Life Scientific Awarded the 2018 Summit Club Channel Partner Award

 

We are happy to announce that Life Scientific has been awarded the 2018 Summit Club Channel Partner Award for Mesa’s Torque product line in recognition of our superior sales efforts and contributions!

At the end of each fiscal year in March, Mesa Labs chooses two partners from each product line that epitomize what Mesa looks for in a channel partner. This includes not only high sales but also a knowledge of the product and superior customer technical support.

There are several factors and attainment that Mesa identified as contributors to recognizing Life Scientific, Inc. for our partnership excellence. These factors include knowledge of the Mesa products that our team is offering, overall commitment to the success of these products, website marketing, cooperative spirit and most importantly, the creative approaches to the development of product and brand recognition throughout our territory.

We are pleased to receive the Distributor award acknowledging Life Scientific’s success and we are striving to reach the next highs as a Mesa Labs valued partner.

For more info on the Mesa Torque Product line please refer to our Torque Testing Webinars, part of the Lunch and Learn Webinar series, or contact our regional representative to provide further info on the product or service of your interest.

COLLABORATIVE INNOVATION: FLEXIBLE ISOLATION TECHNOLOGY INTEGRATED TO FILLING LINES BY FEDEGARI

Berkshire Sterile Manufacturing (US) can be considered the unique CMO that incorporates 100% isolator technology to the filling lines utilizing state-of-the-art equipment. This technology allows to remove the risk of human contamination from the filling and formulation process as highly suggested by FDA, EMEA and other regulatory bodies. Fedegari has proudly collaborated with BSM on engineering a cost-effective and innovative solution that helps pharma industries to advance their product candidate into the pre-clinical or clinical setting.

The result of BSM-Fedegari collaborative innovation is an isolator based filling system that is able to fill the following primary containers: bulk glass vials, pre-sterilized nested vials (glass and plastic) and syringes (glass and plastic), pre-sterilized nested cartridges (glass and plastic), and custom containers (glass and plastic). The system works with both liquid and lyophilized products and the primary containers do not have to be exposed to hydrogen peroxide before entering the isolator.

 

fedegari_sterile_manufacturing_SCADA_integration_isolator_autoclave_oven_filling_line_CMO

 

Air conveyor from Vetromecannica

 

 

The ruggedly constructed Eolo air conveyors are built from thick gauge stainless steel in order to stand up under the most demanding industrial conditions. Air conveyor segments are freestanding and load tested for maximum structural stability. Wherever system routing conditions require special mounting, for example, along ceilings, high above walls, etc., the air conveyor segments utilize appropriate structural supports that guarantee sufficient structural integrity of the plant.
The Eolo air conveyors are single chamber plenums of square cross-section, supporting a bottle channel lower face. The plenum cross sectional area is great enough such that air velocity within the chamber is close to zero. Thus, the static air pressure exhibits almost no loss along the air conveyor length. Local air pressure spikes near fan ports are eliminated by the use of short horizontal baffles at the blower mouths. For cleaning purposes the plenum segments feature bolt-on inspection covers every meter ca. The covers are airtight sealed with rubber gaskets.
Empty PET bottles hang from their neck rings on two parallel rails in the omega conveyor section. Air from the plenum is directed onto the bottles’ finish with a forward-facing vector from jet openings placed at regular intervals along the omega’s internal walls. This air jet is sufficient for accelerating all bottle sizes at speeds from 0m/s to 4m/s ca. in level conveyor sections, as well as for pushing bottles up maximum 10° inclines. Air conveyor lengths are divided into independent segments of not more than 10 meters; vertical end plates seal one segment’s air plenum from the abutting segment’s plenum.

Bonfiglioli Engineering – Quality Control Solutions

Next week in Indiana, accompanied by Bonfiglioli Engineering, we’ll proudly exhibit our comprehensive range of solutions in the field of Headspace gas analysis, Visual inspection and Leak detection solutions.

Headspace Gas Analysis is a relatively new technology to the pharmaceutical industry though it has been well proven in the wine making industry for many years to ensure quality. This technology is non-destructive, non-intrusive and does not contact the product. It can be utilized to quantify a sterile containers physical condition by evaluating its gas headspace including partial pressure, Oxygen concentration or moisture concentration. The laser beam is then passed through the headspace of the container and a sensor evaluates if the laser beam was degraded through absorption by the presence of O2 or moisture in the headspace. This information is compared to the original laser beam power and yields comparative results.

Visual inspection is a mandatory practice for injectable manufacturers to guarantee both quality and patient safety. The finished products must be inspected to identify and reject visible foreign matter contaminated parenteral containers and units displaying defects that could potentially affect product quality. There are companies on the market that still rely on manual visual inspection that is prone to mistakes especially with detecting clear and see thru contaminants in the liquids. Even the most comprehensive and well trained personnel is succumb to errors. Unfortunately injectables and other human consumables aren’t areas we’d like to take risks.

Bonfiglioli Engineering provides dedicated solutions in the markets of Food & Beverage, Plastic, Metal Cans & Tubes, Pharmaceutical, Chemicals & Cosmetics, Aerosol and more, effectively meeting all industrial needs with state of the art technology, including non destructive solutions such as Leak Detection, Visual Inspection and Headspace Gas Analysis, apt for laboratories as well as in-line container integrity testing.

Bonfiglioli Engineering is a part of the TASI Group, the World Leader in leak test and inspection.

Get in touch with our product engineers so they can accommodate a meeting and a live demo on the equipment you might want to see in action.

 

An automation system in accordance to the GAMP5 pharmaceutical standard

By Fedegari, a Company specialized in the design of machines in the pharmaceutical field

 

Part of an international industrial group whose strategic objective is the supply of machines, systems, components and services in the field of contamination control sterilization for the pharmaceutical, biotech and food industries, Fedegari was created by the brothers Giampiero and Fortunato Fedegari in the early 50s in Pavia. Born as a small artisan company dedicated to the production of various carpentry products, it has progressively concentrated on the production of sterilizers, specializing in the design of these machines for application in the pharmaceutical field. In the early 90s, it diversified its production also in the field of supercritical fluid processes (mainly CO2), designing and building systems and machines for extraction and washing processes.

A unique feature of Fedegari is the extreme dedication of the company, which has always rejected the idea of ​​assembling sterilisers and sophisticated machines with commercial grade component. This dedication has allowed Fedegari’s technology to be developed through a deep knowledge of the machines and processes. The same statement is applicable in the automation area when, at the beginning of the 2000s, Fedegari started to develop the current platform starting from a sophisticated operating system (Wind River’s VxWorks).

 

Integrated cutting-edge system

Thanks to the collaboration with SEW-EURODRIVE, Fedegari has created a sterilization plant with an integrated and robotized handling system for parenteral solutions in bags (FEDEGARI AUTOMATIC HANDLING SYSTEM FOR FLEXIBLE BAGS) which will soon be delivered to an important US customer. The system integrates the palletization of the product coming from three filling lines, through several robot cells (delta and anthropomorphic) with automatic feeding to two autoclaves with superheated water of large dimensions (cylindrical chamber with a diameter of 2400 mm x 14500 mm in length). These sterilizers are able to load 24 pallets of 20 trays.

The plant is managed by an automation system made up of 3 PLCs (area handling, robot loading area and unloading robot area) that integrate the control and safety on an Ethernet fieldbus and talk with 16 robot controllers and a supervision SCADA . In the system there are 5 vision systems for the pick & place controls of the delta robots.. The system has a vertical integration with the MES for the production batch management and the customer HISTORIAN for the collection of production and sterilization data. The autoclaves are managed in an integrated way with the Fedegari Thema4 control system. SCADA server software is virtualized in the customer’s IT with all services (remote authentication, SNTP synchronization and HW and SW asset management) with the presence in the field of 3 fixed and 1 mobile client stations. The plant is connected to the Fedegari after-sales support.

The word to SEW-EURODRIVE

The MOVIGEAR mechatronic drive on board the system

Fedegari was facing a new technological challenge as it was approaching issues like those of handling, but Sew is a partner that is capable to support the most appropriate architecture for top level performance required by the end customer. Detailed mechanical and electronic sizing, design support, commissioning and product training courses were carried out to better familiarize the clients with the equipment and procedures

By working with the engineers at SEW, the Fedegari group has centered its project objectives and appreciating SEW’s expertise, quality and organization. Fedegari intends to continue its partnership with SEW-EURODRIVE so that new projects for the future are already being developed

 

FEDEGARI: in the name of verticalization

“The company has always been oriented towards innovation – explains Paolo Fedegari, managing director of the group. Fedegari differs on the market by virtue of the numerous innovations introduced both in the field of machines and in processes, as well as for the extreme verticalization of production. We have always refused the idea of ​​assembling our machines with commercial components”, concludes Fedegari.

Join Cozolli at INTERPHEX 2018

 

Cozzoli Machine Company will be exhibiting at INTERPHEX 2018 from April 17 – 19, 2018 at the Javits Center in New York City, NY USA. As a single source provider for individual components to fully integrated lines, we offer production solutions for every application, from pharmaceutical, cosmetic, e-liquid, health, beauty aids, personal care, food and beverage, chemical, paint and industrial products. Stop by to see our latest technology in Booth 2805!

 

Featured machines include the RPF8 Rotary Piston Filler, the FSV50 Mini Monoblock, the GW24 Ampule/Vial Batch Washer, and the PF2-IS powder filler. We will also be showing our tabletop F400XSS Liquid Filler.

 

To set up a booth meeting, please contact us at (732) 564-0400 or sales@cozzoli.com. We look forward to seeing you at the show!

 

 

MACHINES ON EXHIBIT


Fast, flexible, and reliable, our 
RPF Rotary Piston Fillers are fully automatic machines, most recently designed to accommodate the different viscosities in cough syrups. The RPF is available in different frame sizes and models; the standard 2.75″ diameter cylinders and pistons provide fill ranges of 5 to 21 fluid ounces, with 4 to 36 filling nozzles, and speeds of 60 to 540 CPM. Overhead driven pistons feature a fine fill adjustment, achieving ±0.5% fill accuracy and are easily removed for cleaning and changeover. Read more…

 

The FSV50 Mini Monoblock is a small, reliable, high performance machine designed for processing vials in laboratory, clinical production locations or other areas with limited space. It is designed for use in a clean room environment, with hood isolation and laminar flow in mind. Designed to fill liquids or powders, then stopper or cap the containers at speeds up to 50 vials per minute, the Mini Monoblock is capable of covering a range of vial sizes from 1ml to 100ml. Read more…

 

The Cozzoli GW24 Batch Washer is a high production vial and ampule cleaning machine, designed for years of reliable operation. Using a PLC to control the wash cycle, the wash parameters can be programmed into the machine for individual wash cycles. Up to nineteen different wash recipes of 99 steps each provide for individualized customer requirements. All wash recipes can be password protected. Read more…

 

The PF2-IS Powder Filler is designed to promote the highest level of performance for accuracy, repeatability and easy cleaning. Totally enclosed product pathway with no abrading parts ensures zero powder contamination. Fine tuning fill-volume adjustments can be made on the fly without tools. This machine is configured for use in an isolator. Read more…

 

F400X-SS Single Piston Filler is your machine for filling liquids at low production rates with high accuracy. Fills aqueous solutions to light oils, easy to clean and sterilize, and is designed for rapid changeover. Read more…

 

 

FIND COZZOLI BOOTH AT INTERPHEX 2018

 

Members of the Cozzoli team including engineers, sales, technical service and management will be available at INTERPHEX booth for discussion. Bring your application to Booth 2805.  

 


 

View Show Map

 

Live Demos for Headspace Gas Analysis

The final week of March in Indiana, accompanied by Bonfiglioli Engineering, we’ll proudly exhibit our comprehensive range of solutions in the field of Headspace gas analysis, Visual inspection and Leak detection solutions.

We have the Bonfig LaserCube with us and it will be available for live on site demos upon request. It’s a state of the art non-destructive, non-invasive laser-based inspection technology for measuring the headspace level of gases, such as oxygen and carbon dioxide, as well as monitoring moisture levels. The inspection method is created to meet specific customer requirements offering extreme stability and accuracy in inspection even where the headspace is limited. The Laser Cube is a compact and lightweight system that is easy to use and set up via integrated PC and any wireless touchscreen tablet.

This type of testing and inspection is highly applicable to facilities producing sterile drug products packaged under modified atmosphere or vacuum as Oxygen sensitive and Lyophilized products.

The LaserCube uses Tunable Diode Laser Absorption Spectroscopy method which gives highly accurate readings of both moisture and oxygen levels.

 

 

Key benefits and differentiators of the LaserCube

  • Non-invasive and nn-intrusive inspection method
  • The tecnology is design to make Etalon effect egligible
  • Fast, reliable and repeatable results
  • Nitrogen purging is not required during oxygen measuring
  • Compact and durable design
  • Maintenance-free & quick changeover
  • Cost-effective solution with low power consumption
  • Fully automated test cycle sequencing with manual loading and unloading of containers
  • Data can be stored and exported (production, raw data, events, alarm)
  • Enhanced easy-to-use HMIU integrated functions
  • HMI real time display of statistics and raw data
  • Computerized system is designed to comply with FDA 21 CFR Part 11 and EU Annex 11
  • Validation package guarantees complete and efficient regulatory compliance

Exclusive Spring Offer from Cozzoli

Cozzoli is extending an exclusive offer to our customers for the month of March. Take advantage of a 15% discount on parts and service and ensure your Cozzoli and MRM/Elgin machines are in peak condition!

 

Our Project specialists can schedule performance evaluations and help get you the best deal on commonly used machine parts.

 

Contacts us today to take advantage of this limited time offer! Either call Customer Service at 800-829-5741 or email JoeS@Lsi1.com.

Offer Includes

  • 15% discount on parts
  • Discounts on preventative maintenance

CLICK HERE for more information on Cozzoli-MRM/Elgin parts & service

 

*Some restrictions may apply

 

Contact Tech Support

 

Have any other questions about your Cozzoli or MRM/Elgin machines? Get answers from our tech support team!