Filling Methods by Cozzoli machines

For almost a century, Cozzoli Machine Company has provided technologically advanced machinery for the packaging industry. Till today Cozzoli has developed a variety of filling methods to meet your production goals.

Cozzoli offers inline or rotary filling with piston, peristaltic pump, diaphragm pump or time pressure technology. Choose continuous or intermittent motion, stand alone or monoblock configuration. Every Cozzoli filler provides unmatched ease of container handling and change-over. Provided below are the different Filling Methods that can be carried out with Cozzoli filling machines.

 

Fill – to – Level

Fill-to-Level fillers are especially suited for thin and foamy products, like cleaning solutions for example. These fillers compensate for variations in container volume while retaining cosmetic fill accuracy. All of this fillers operate on the principles of gravity, pressure and vacuum.

 

Time Pressure

Time Pressure filling is accomplished by controlling the flow of the product through the tubing. By design, the product stays in the manifold that feeds the tubes. A computer calculates the product flow time needed based upon manifold pressure, nozzle size and target fill volume.

 

Piston Filling

The Piston fillers can have industrial and aseptic applications. Piston fillers are ideally suited for filling a diverse range of products. These fillers are ruggedly designed yet precisely built for long trouble free operation. The piston product viscosity range can be from 1 to 100K centipoises and with slight customization even above that.

 

Peristaltic Pump

Peristaltic pump is a system where nothing but the tube touches the fluid eliminating the risk of the pump contaminating the fluid or the fluid contaminating the pump. The complete closure of the hose, which is squeezed between a shoe and the track gives the pump its positive displacement action preventing backflow and eliminating the need for check valves when not in operation.

 

Diaphragm Pump

Diaphragm Pump fillers are suited for corrosive chemicals, abrasive materials and delicate liquids. These are also used with blood, insulin and plasma filling systems. The Diaphragm pump is a completely enclosed system that eliminates air bubbles on small fills and features accurate repeated fills.

 

Rotary Time Pressure

Time pressure fillers are well suited for filling heavy viscosity products. The nozzle is open to the product for a specified amount of time to achieve proper fill volume. Proper fill is dependent on three critical areas: time of fill, pressure of the flow and filling speed.

 

Vacuum Powder

This totally enclosed system removes the possibility of product contamination. Fill volume of each piston can be independently adjusted during operation. Two to sixteen stations are available. Multiple dose fills are ade possible by simply setting the preferences on the micro-processor. This also provide a solution to product loss due to dusting issues that is virtually eliminated.

 

Call 800-829-5741 to inquire about pricing and to obtain additional info on the different filling and pumping systems developed by Cozzoli.

Thema4 Process Controller by Fedegari

In order to meet the most demanding pharmaceutical requirements, great care has been taken in designing Thema4 life cycle management: from the conception phase to components selection and definition of system architecture and project management, through the project phase in the development of software according to the FDA CFR 21, part 11, to the current operation phase and the definition of product management procedures (change control, configuration management, support, repair, maintenance, etc.) according to the GAMP guidelines.

 

Now, after continuous improvements of software and hardware components, functions and processes, Thema4 finds itself in the maturity of the operation phase and the reference guideline for its management is the GAMP 5. Several new software versions are released every year that include those developments requested or suggested by our end users.

That’s why investing in a sterilizer with a Thema4 process controller allows the buyer to capitalize on decades of cumulative experience in managing pharmaceutical manufacturing processes developed for the most demanding companies worldwide. An extensive team of experts assures that the controller is constantly innovated and manages all new developments in accordance with the end users needs and the adopted GMP standards.

 

The Thema4 main features and functions will be furtherly explained on our upcoming webinar scheduled to be aired on July 18th at 10:45 AM CST. Basically our Presenter, the newly appointed Automation Director at Fedegari, Massimo Ghelfi, will explain the process controler high performance, fully validated control system, with the highest level of flexibility and configurability to fit all end users needs COTS hardware, reliability and performances.

 

If you are interested in learning what is the process control main application and which products can be integrated into its operation, then this webinar is for you.

Bellows Bottle Filler and Capper machine for SALE

We at Life Scientific, Inc. are pleased to inform you that we have available a second hand Filling and Capping machine for Bellows Bottles.

The machine that we have was only preowned by LF of America and is manufactured by Comas. The machine was designed to fill LF of America’s Bellows bottles but it can be easily modified to handle other types of packaging.

 

The machine has a capacity of filing and capping 1.500 units per hour or 25 units per minute. It uses a vibratory feeder that sources the starwheel with bellow bottles. Another feeder moves the caps to the second star wheel. The filler is easily customizable and can be modified to fill powders.

The machine filling range starts from 2ml and up to 10ml and it’s carried out with a piston filling system.

This machine and packaging type is great for packaging powders (hemostatic) and drugs for vaginal/rectal usage. The machine can be upgraded to close the containers with tamper-evident cap.

After capping, the filled units are loaded onto a conveyor that adds the opportunity for coating the packaging on the bottom.

 

The Machine that we have was built in 2003 and has filled several million units and has only been operated in the LF of America ISO 8 Cleanroom.

 

Call 800-829-5741 to inquire about pricing and to obtain additional info on the product.

 

Popular New Liquid Packaging Trends in 2018

 

Contract filling and packaging solutions for liquids cover everything from food and non-food substances to over-the-counter (OTC) medications, pharmaceuticals, and more. The large size of different companies in need of these services has introduced new liquid packaging trends that are now being embraced by companies around the world.

Turnkey packaging solutions and multi-layer containers are two such examples commonly found in the current market. Both of these are direct responses to consumer demands and prove that the company selling the product is listening to their customers. Let’s examine all of the latest liquid packaging trends by covering the different benefits each individual trend offers.

The Rise of Turnkey Solutions

Turnkey solutions are becoming the norm for pharmaceutical companies in need of packaging their medications and OTC products. Contract packagers have evolved into a multi-billion dollar industry and their growth is only projected to increase year to year. This is a direct result of their all-in-one services that not only achieve the desired results but at a reduced cost. In other words, it is the better investment for growing companies.

Key benefits include:

  • Cost-reduction
  • Scalability
  • Quality assurance
  • More eco-friendly
  • Maximum value
  • Standard regulation compliance

Tip: Since turnkey solutions are among new liquid packaging trends, more companies are trying to quickly adapt. Choose your turnkey partner by verifying their history and looking for a proven track record of success first.

Creative Custom Packaging Designs

Knowing the consumer market is key when deciding on the package design. For example, organic items have been the preferred choice for consumers across most industries. This preference has revealed a simple pattern in labeling. In essence, the more modest and natural the packaging seems, the more appealing it is to customers.

Other packaging and label preferences include:

  • Functionality (Is it portable/ sealable/ recyclable/ etc.?)
  • Clear / transparency (Can you view the product through the container)
  • Eco-friendly (Does it reduce overall environmental impact)
  • Vintage labeling (Can you revive an older design for nostalgic appeal?)

Tip: The most important aspect to deciding on the packaging design and labeling is to know who you are marketing it to. Bold is not always better and a minimal design strategy can save you money.

Embracing New Technology

The improved capabilities of automated contract filling machines are equally economical and practical. Why potentially risk damaging your product during the filling process when it is unnecessary? The temperature when sealing can damage or negatively affect the product’s quality. Moreover, more companies are in need of small batch product sizes than ever before.

Contract filling services using injection molding technology during the blow, fill, seal process eliminate this risk and new, automated contract filling machines are capable of both full-scale and small batch production. What this means is you can eliminate paying excessive labor costs if you need to.

To learn more about the advantages of contract filling using injection molding, check out Contract Filling Equipment for more information.

 

To discuss these liquid packaging trends or to speak with someone about the advantages of using a turnkey partner connect with us or contact LF of America today.

A member of our team will be more than happy to find the perfect packaging solution that brings your company into its next phase of success.

 

Bonfiglioli in Minnesota

 

We are delighted to announce that as of Monday June 25th we will be travelling around Minnesota accompanied by Bonfiglioli’s Product Specialist Piero Polastri.

Due to the opportunity of our Project Managers being in your close proximity, we strongly encourage you giving us a call and getting your name on our site visits calendar.

 

This Bofiglioli Demo Tour will uncover some insights on the just released new SAIL machine.

The Bonfiglioli Engineering SAIL puts Container Closure Integrity Testing, Visual Inspection and HGA all on one tabletop making it the ideal solution to ensure Quality and Safety of Parenteral Packages and verify:

– Presence of leaks

– Headspace gas content

– Absence of visible foreign materials.

It is suitable for in-process control, clinical trials and laboratory use without altering the container features. Testing is quick, reliable and repeatable, and gives consistent results for a comprehensive batch control.

 

SAIL stands for Smart Automated Inspection Laboraty meaning that the machine is an automated inspection laboratory especially designed to conjugate sensitivity performance, productivity as well as flexibility to inspect different container types, sizes and contents. A single machine designed to provide customers with a comprehensive set of benefits.

 

Based upon the Bonfiglioli Engineering state-of-the-art proprietary technologies, SAIL is fully customizable in order to best meet present and future user needs and cover a wide range of inspection requirements.

It is characterized by complete modularity and flexibility, including one or more stations for Automatic Visual Inspection to perform any kind of foreign particles detection, cosmetic analysis and cap control at 360°. Additionally, it can integrate stations for Vacuum-Decay based CCIT and Laser-Based HGA for Oxygen/Moisture/CO2/ Vacuum level control, thus making this product an all in one inspection solution suitable for various production facilities.

 

If you want to get some early insights on the SAIL machine as well as on other products off the Bonfiglioli Engineering product line get in touch with Joe Skorcz at JoeS@Lsi1.com or 312-545-2164.

 

Don’t miss out on the opportunity to be first in line to learn more about the newest innovation in the automation inspection for various containers.

The Most Efficient Unit Dose Packaging Machine Available

 

 

 

 

LF of America offers their brand new PENTAFIL unit dose packaging machine that is capable of filling, sealing, and packing liquids for a variety of different industries. While LF provides contract packaging services for orders small and large and are able to create custom packaging, being part of the Internationally renowned Lameplast Group enables LF to assist companies worldwide. Our latest filling and sealing unit dose packaging machine is named the PentaFill A25. Its impressive capabilities include filling as many as 125 vials between the sizes of 0.33-1.0 ml per minute and 115 vials between the sizes of 2.0-10.0 ml per minute. As such, this efficiency is top of the market and perfect for preparing large distribution orders.
For smaller orders, we utilize a similar, comparable machine named the PentaFill A10.

For huge production lines, We would recommend the PentaFill Twin 25 that is capable to double the performance of the Automated PentaFill A25. The new Twin 25 machine is suitable for Contract filling facilities. These fillers are using injection molding technology combined with the blow, fill, and seal process to give users many added benefits. The best contract packaging companies use the flexibility and efficiency of these automated packaging systems to their advantage. The PentaFill Twin A25 is capable of matching the production output of a BFS machine thus making it perfect for contract fillers.

LF’s unit-dose and automated liquid packaging systems use injection mold technology instead of the “Blow Fill Seal” process. Injection mold technology offers companies various benefits unmatched by blow fill seal machines.

Bonfiglioli Engineering unveiled the brand new SAIL – SMART AUTOMATED INSPECTION LABORATORY for pharmaceutical applications.

Earlier today, Bonfiglioli during the opening hours of this year’s Achema Expo in Frankfurt, Germany unveiled their latest product for the pharma applications. It is capable of performing multiple in line inspections on the same package container. By design it features in line leak detection, visual container inspection and laser analysis.

To learn more about the Smart Automated Inspection Laboratory – SAIL give us a call or contact MarkoV@Lsi1.com

MesaLabs Manual Cap Torque Analyzer

 

The Sure Torque Series of Manual Cap Torque Analyzers are designed to measure application and removal torque of bottle caps up to 50 lbFin [5.65 Nm]. They feature adjustable posts that effectively grip a broad range of container shapes and sizes, while optional flat and adjustable jaws are available for unique profiles.

The ST-H0X Manual Tester is recognized by its rugged aluminum design, and simple, intuitive operation allow for use in laboratory and production environments.

Mesa Labs’ Manual Cap Torque Testers are known for their class-leading accuracy of ±0.3% and blazingly fast sampling rate of 7,000 Hz which ensure reliable and consistent test results, even in quick-action applications.

The ST Series includes a range of sophisticated productivity-enhancing features, including USB, RS-232, Mitutoyo, and analog outputs, automatic data output and zeroing upon cap removal, memory storage for 1,000 readings, pass/fail indicators and outputs, and more.

Password protection is provided to prevent unauthorized changes to settings and calibration.

The ST Series of analyzers include MESURTM Lite data acquisition software. MESURTM Lite tabulates continuous or single point data. Data stored in the unit’s memory can also be downloaded in bulk.

Another important aspect of this product is the one-click export to Excel for further data manipulation, which makes the ST-H0X compliant with the FDA 21 CFR Part 11.

Interested in seeing this equipment or other torque testers in action, please get in touch with our regional representatives and we’ll get you on our agenda.

 

Bonfiglioli at IPACK IMA 2018

At the upcoming tradeshow, the IPACK IMA 2018 in Milan, Italy starting tomorrow May 29 Bonfiglioli Engineering will present their innovations in leak detection machinery. The Bonfiglioli Engineering range of non-destructive machines offers 100% Inline and offline leak detection for bottles, doy packs, food cans, ready meals and stick packs using Force Decay, Lid Deflection Vacuum and Pressure Decay methods. Solutions are available also for Automatic Visual Inspection of containers and Headspace Gas Analysis for MAP Packages.

Bonfiglioli’s products have broad applications and are huge contributors to the ever improving food safety challenge. This package integrity validation technology has been developed by Bonfig to address the growing need of the industry to validate the integrity of a package prior to food packing. Initially, the focus was on hot dog and sausage packages, but updated regulations are now being targeted to several other package formats, including bacon, sliced meats, cheese, and other forms of vacuum formed packages.

Leak detection machinery is not a simple technology, but a combination of various technologies dependent on the requirement. Vacuum, vision, and several other sensor technologies can be integrated to detect seal contamination, leaks, pin-holes, and other elements leading to loss of package integrity.

Food package inspection is typically a pass/fail selection, but in some cases such as the FDA 21 CFR Part 11, statistical information can be gathered and reported to determine online or offline process improvements. Rejected packages are typically not packed and flow through the system into totes or exit conveyors.

 

Stop by Bonfiglioli’s booth HALL 5 – BOOTH C17 at the IPACK expo at Rho Fierro Milano if you happen to be touring across Europe or contact us if you need help to solve your food packing integrity needs!

Differences Between Injection Molding & Blow Fill Seal

Injection Molding Technology + Fill & Seal

  • Two-step process that molds vials then transfers them to the filling line to be filled and heat sealed. (No risk of contact between product and heat)
  • Added flexibility that ranges from small batches at 1,500 vials per hour to full-scale production at 15,000 vials per hour.
  • Smaller dimensions mean machines fit in most existing contract filling environments.
  • Improved end-user experience. Easily switch out or replace damaged, worn, or old parts.
  • Less than half of the cost of traditional BFS machines with the same production capacity.
  • More environmentally friendly and no excessively wasted plastic material.
  • Provides the option for multilayer packaging designs and calibrated drops.

Blow Fill Seal (BFS)

  • One-step process that blows and fills vials at the same time. (Risk of contact between product and heat)
  • Only capable of full-scale production at roughly 10,000 vials per hour without being able to stop the machine. 3 working shifts necessary once started.
  • Large dimensions with a recommended minimum room size of 500-600 square feet.
  • Halted production time due to the changeover of molds.
  • Higher initial financial investment and overall cost.
  • Large amount of plastic waste is cut from the parison and then disposed of.
  • Extremely complex set up, maintenance, and operating instructions that require highly skilled and well-trained personnel.

LF of America uses the most advanced contract filling equipment to fulfill orders big and small. They also manufacture the Pentafill innovative liquid packaging machines and distribute the most highly advanced contract filling equipment available. These unit-dose and automated liquid packaging systems use injection mold technology instead of the “Blow Fill Seal” process. Injection mold technology offers companies various benefits unmatched by blow fill seal machines as shown in the bullet points above.

 

To request a free product sample or to speak with one of our team members about packaging services or manufacturing contract filling equipment contact our representatives.