CLEANING GUIDELINES VALVE ASSEMBLES AND SYRINGES

Regularly scheduled preventive maintenance minimizes downtime and assures trouble-free operation!M

Cozzoli’s exclusive sliding valve assemblies and precision honed syringes are mated for life and operate as matched sets on liquid fillers.

Each set is engraved with matching serial numbers that correspond accordingly. It’s important never to mix up or interchange designated serial numbers with other valves and syringes, as damage and poor operational permanence will result.

DISASSEMBLE AND ASSEMBLE

When disassembling, always withdraw the piston in a straight, horizontal line in reference to the valve or the syringe body.

Reverse this procedure to assemble.

Never use force, as it will cause the components to jam.

BEFORE USING

Before the initial use of valve assemblies and syringes, clean and rinse with a solution of soap and water, then flush thoroughly with clean water.

Place them on a lint-free cloth or paper.

Do not allow components to come in contact with contaminants or other metal parts after cleaning.

AFTER USING

Product should not be allowed to dry in the valves and syringes since it could cause them to score or seize.

Always disassemble them and clean properly with an appropriate solution that will remove product.

A bristle brush with a plastic center may be used. Blow dry components thoroughly to ensure that they are free of foreign particles and watermarks. When autoclaving, be sure that the piston is removed from the valve or syringe body.

WHILE IN OPERATION

Valves and syringes should never run dry while in operation. Either product or water must be present.

HANDLE WITH CARE

Proper valve and syringe handling is essential. Dropping, hammering on or restraining them in a vise may damage and render them inoperable.

PRIOR TO INSTALLATION

Check action of valve and piston within syringe cylinder to ensure smooth performance prior to installing on filler.

STORAGE

Between uses, valves and syringes to be stored wrapped in a lint-free cloth or paper.

This is necessary to avoid contamination and contact with other metal components.

Contact our offices to learn more about Cozzoli Machine Company and their comprehensive product line.

Contract Filling Services For Liquids

Reliability is a necessary trait in the packaging industry. If you aren’t able to depend on the contract filling services you require for distribution, it’s your own business’ reputation that hurts.

Without proper handling, your product could become less effective or end up becoming tainted. Contract filling companies need to have access to the right resources and carefully developed plans to ensure product safety.

This is as true for health and beauty products or cosmetics, for pharmaceuticals and diagnostic products. Simply put, you need a packaging company you can trust to handle your products safely from end to end. We are that solution.

Your Source For Reliable Contract Filling Services

LF of America is the leading provider of contract filling services and liquid packaging solutions in the US. Our team of technicians believes that each time a client entrusts us with handling their products, we become an extension of their business.

For this reason, we put a strong emphasis on safety and compliance during the filling process. It’s important to us that each and every one of our clients knows they can rely on our contract filling service to be done safely and on schedule.

In order to accomplish this, our contract filling services are handled in our state of the art facility within contained settings. We have access to some of the most advanced automatic filling and sealing machines available, which are equally capable of handling small batch orders all the way up to full-scale production sizes.

The filling and sealing machines are stationed inside our ISO-8 cleanroom. The ISO-8 cleanroom is immaculately maintained in order to remain in total compliance with Cosmetic GMP regulations, an extension of the Quality System Requirements for medical devices.

Our contract filling services regularly handle each of the following:

  • Liquid Cosmetics (Most viscosities, including creams, gels, powders)
  • Gel & Liquid Diagnostic Products
  • OTC Pharmaceuticals
  • CBD Oils
  • Veterinary & Animal Care Products

For packaging options, our contract filling services can be performed using your own existing containers or you can choose from our diverse variety of packaging types. Our collection of innovative packaging options include unit-dose packaging, Bellow Bottles, wand tubes, enema containers, bottles with droppers, dual chamber bottles, and more.

All of the different types of options available through our packaging manufacturing department are suitable for many different applications. Please fill out an inquiry form to request our help with developing a unique packaging solution that is ideal for your intended purposes.

If you would like to receive a free estimate regarding the cost of our contract filling services, call our office at 800-829-5741.

Table top Container Closure Integrity Tester

The LF-S11 by Bonfiglioli is a countertop compact machine, designed for Non-Invasive, Non-Destructive Container Closure Integrity Testing of diverse types of Pharmaceutical Containers filled with liquid, lyo, powders, etc..

Suitable for In-Process Control and Laboratory use without altering container and/or content features.

The integrated software system allows full compliance to provisions stated in FDA 21 CFR part 11 as well as EMA Annex 11.

3 Configurations of the machine available to meet all specific requirements:

– BASIC, for most of the container formats 

– XL, designed specifically for large formats (more than 100ml)

– SY, designed for syringes, carpoules including automatic plunger stopping device

Equipment test method complies with:

– FDA Guidance for Industry “Container and Closure System Integrity Testing in Lieu of Sterility Testing as a Component of the Stability Protocol for Sterile Products”.

– United States Pharmacopoeia General Chapter «1207» “Packaging Integrity Evaluation”.

– EU Guidelines to GMP Medicinal Products for Human and Veterinary Use – Annex 1 “Manufacture of Sterile Medicinal Products”.

– PDA Technical Report No. 27 “Pharmaceutical Package Integrity”

All dedicated test chambers are designed according to the container characteristics for a maximum of leak detection sensitivity and are monitored by specially developed electronics during the testing process. The group has been recently redesigned to obtain improved functionality (quick

 single-handed opening and closing). It is directly installed onto the Testing Chamber supporting flange and it is composed by: – A fixed bottom part; – A removable top cap (upper part) that allows plugging up the testing group corresponding to Container loading and unloading operations.

HOW IT WORKS

The test chamber fixed bottom part is equipped with a mobile piston, plunger stopping device (PSD), having vertical motion between two limit positions, “upper” and “lower”, and having a section equal to that of the PFS plunger.

The initial vacuum, generated in the test chamber, produces an upward movement of the PSD.

The same “upper” position is kept until the second reading; at that time, the action of a dedicated pneumatic actuator provides for exhaust of vacuum in the test chamber bottom area and produces the PSD downward movement towards the “lower” position.

For more information, please call our office and we’ll be happy to assist.

Lunch and Learn webinar series

If you want to learn more information about the equipment and machinery that is manufactured by the companies we represent, To meet the team of engineers behind the projects and hear their thoughts and opinions on some of the critical processes that they were challenged with, then the Lunch and Learn Webinar Series will be a good place to start.

You’ll also have the opportunity to learn about the key features of specific products and equipment and what is their proper application.

Among the most viewed topics we discussed on our webinar were:

  • The never ending debate of Injection Molded Unit dose delivery systems versus the Blow Fill Seal containers;
  • The discussion of proper storage methods, Standalone Freezers or Consolidated chambers;
  • The presentation on the Key Factors of the development of a Cleaning Strategy;
  • The often overlooked issues with quality control equipment and solutions;
  • A nice presentation of the applicability of Torque testers on the Pharma Market;
  • The important part that conveyance plays in your production efficiency;
  • and you can find a lot of case studies and machine demos in each episode of the Lunch and Learn Webinar Series.

Our Webinar Broadcasts are always public, free to attend and comment. In order to receive updates about any upcoming streams of our Webinar you can Subscribe to our Website, Connect with our LinkedIn Page, or Subscribe to our YouTube Channel.

If you have any special Requests about some topic being discussed on the series, have questions about any previous streams or you’d like to inquire more information about any aspect of the series, please send an email to Marko via MarkoV@Lsi1.com

Happy New Year!

New Year is upon us again.

So accept these season’s greetings that we happily send. Thank you for always providing great solutions and for being the one to bring forth excellent resolutions and challenges to our team.

You are valued as our business partner.

To our team you bring so much wisdom, fun and laughter.

Happy New Year from the LSI Team.

r is upon us again.

So accept these season’s greetings that I happily send. Thank you for always providing great solutions and for being the one to bring forth excellent resolutions.

You are valued as a business partner.

To our team you bring so much wisdom, fun and laughter.

Happy New Year from the LSI Team

Happy Holiday Season

May the Holiday season fill your home with joy, your heart with love, and your life with laughter.

Wishing you peace, love, and joy this Holiday Season and throughout 2019.

Wishing you Holidays filled with fun and laughter, and very best wishes for a prosperous new year.

Merry Christmas and Happy Holidays

As the holiday season is upon us, we find ourselves reflecting on the past year and those who have helped to shape our business. It’s been quite a year for us all!
We hope that 2019 has been just as memorable for you, your colleagues and your loved ones. We look forward to working with you in the years to come.

Seasons Greetings. May your holidays be merry and bright.

Let us take this opportunity to thank you for all your faith and dedication towards our company, on this Christmas.

Hope your bond lasts forever.

Merry Christmas!

Walk in Chambers – The future of storage

Bahnson Environmental specialties designs, manufactures, installs, and services custom chambers of all types and sizes, for a wide array of applications, including: GMP Shelf-Life Testing and Storage, Dry/Moist and Cold Storage for Seed and Agricultural Products, Nutritional Supplements, General Materials Testing, Mold and Fungal Incubation, Photography Storage, Concrete Curing, Roll-In Bottle Incubation Chambers and Cold storage solutions.

They are part of the EMCOR group a fortune 500 company with over 40 years of extensive experience in the field, providing the most resource-saving technologies in liquid-circuited cooling systems to ultrasonic humidification.

When custom solutions are required, the engineering team has the training and experience to ensure that optimal performance does not sacrifice energy efficiency. In their comprehensive experience they have encountered facilities that had lost multi-million dollar worth of research due to freezer or consolidated chamber failures.

In the recent years, Bahnson Environmental have become advocates for installing a consolidated walk in chamber over solving your storage problems by adding a new stand-alone freezer and ending up with the so called freezer farm.

The debate of Freezer farm vs Consolidated Storage has been showcased on our webinar series. Some of the more specific conclusions reached on that show were:

  • Freezer Farms are cheaper to be bought and are easier to be installed
  • Freezers are more prone to failures over Consolidated walk in chambers
  • Freezer farms have significantly higher maintenance fees
  • Freezers are less power efficient than consolidated walk in chambers
  • Freezers often have no to low fail safe assurance technology
  • There are no minimal or maximal space requirements in installing walk in chamber
  • Under some external third party studies 4 common ultra low freezers have the same power efficiency grade as a walk in chamber 20 times that size in volume

Bahnson’s standard and custom environmental chambers / rooms include:

  • Walk-in temperature and humidity chambers
  • Walk-in warm rooms
  • Walk-in cold rooms
  • Walk-in freezers
  • Walk-in incubators
  • ICH stability chambers
  • Shelf life study chambers
  • HEPA filtered clean cold rooms
  • HEPA filtered clean warm rooms
  • Test chambers
  • Plant growth chambers
  • Shelf lighted rooms
  • 1% and 2% dry rooms
  • Other low humidity dry rooms

These are just a sampling of room types included in the walk-in environmental chamber series.

In the pharmaceutical market, Bahnson is determined and focused on stability rooms, that strive on meeting and exceeding the ranges and uniformities of the ICH has allowed Bahnson to become the recognized leader in chamber design, construction, and stringent performance qualification in support of our clients’ validation.

Bahnson is also a well know brand that supplies universities, medical schools, and industrial customers with chambers requiring uniform dependable room conditions for storage and testing experiments.

Their comprehensive resume includes some of the largest installations of multiple environmental rooms in notable research buildings on campuses throughout the US.

 

Get in touch with our project engineer at 800-829-5741.

 

Cosmetic Filling And Packaging

LF of America provides cosmetic filling and packaging services for a variety of liquids, creams, lotions, serums, and powders. Our cosmetic contract filling services are done using state-of-the-art liquid filling machines that are can be used for small batch orders all the way up to large-scale production sizes.

We also provide a wide variety of different cosmetic packaging options that will perfectly accommodate your product so that it is safe for distribution and appealing to consumers. The cosmetic packaging options we provide include everything from unit-dose packaging for easy, precise delivery to dual chamber bottles with tamper evident caps, and more.

Find out more about what is all included in our cosmetic filling and packaging services below. To get started today, contact LF of America and let us prove to you why we are the best turnkey partners in the cosmetic filling and packaging industry.

 

LF of America is proud to say that contract filling for cosmetics is one of our primary specialties. We take great pride in our impressive ability to fill and seal cosmetic products in accordance with the best industry practices for assured product safety and quality.

The process is performed on-site in our state of the art facility, which houses advanced liquid filling machines in completely controlled areas. Our ISO-8 cleanroom is in accordance with all Cosmetic GMP regulatory guidelines, extending from the Quality System Requirements for medical devices.

The filling machines for cosmetic liquids and creams can handle most liquid viscosities and the line speeds can work at different rates, meaning no order is too big or small or us to handle. In addition, we are capable of filling your own packaging design or you can choose one of our cosmetic packaging options.

These packaging options include unit-dose packaging for cosmetics, wand tubes with hypoallergenic applicators, dual chamber bottles, bottle with droppers, enema containers, containers for vaginal use, and the diversely unique Bellow Bottles complete with various applicators and different size cannulas.

Turnkey Cosmetic Filling And Packaging Services

Our cosmetic filling and packaging services are truly all-inclusive and include everything from formulation, batching, packaging selection, and filling. We also offer packaging manufacturing and provide custom packaging options where we will hot stamp, emboss, and label, and pad print your product before distribution.

It is our mission to guarantee satisfaction for our customers and our shared goal is to help our clients succeed in their venture, however big or small. Whether your need is to test out a new line or prepare a best selling product to meet consumer demand, our cosmetic filling and packaging services can help you get it done quickly and affordably.

Give us a call to ask us more about the premier choice in contract filling at 800-829-5741 to get started today.

 

AirTech – BENEFITS OF VETROMECCANICA’S AIR CONVEYORS

Air conveyor belts are highly recommended to convey empty PET bottles/containers without damaging them.
Vetromeccanica’s air conveyor belt guarantees the hygienic, gentle and safe handling of empty PET bottles even at high speed, indeed.

The Air conveyor has been Vetro’s flagship model since their launch in 1992. It is a solution that they have delivered to hundreds of customers in more than 70 countries worldwide. The AirTech system it The model that is designed and built only by Vetromeccanica and listed below are some of the key features and benefits of running an Air conveyor over any other solution.

– FAST AND FLEXIBLE ARRANGEMENT 
AirTech can be easily installed on the wall, on the ceiling or on the floor according to the production plant needs, structure and resources

– EASY AND FAST FORMAT CHANGE-OVER  
Thanks to its special guides adjustment system this air conveyor belt can handle every bottle format, as it utilizes an approach of hanging the bottles down holding by the neck of the PET bottle.

– AIR FLOW ADJUSTMENT 

According to the bottle format to be conveyed. This feature can be used as a clinical buffer when you need to diverse or accumulate a minimal or maximal line accumulation.

– INTUITIVE AND TOUCH SCREEN HMI 
Facilitated monitoring operations and adjustments: intuitive and easy to use HMI.

– MINIMAL MAINTENANCE COSTS

Mainly because the whole guidance system is built from stainless steel and the deteriorating elements are reduced to the bare minimum.

– ENERGY SAVING LOGIC
Reduced energy consumption of just having a couple of fan blowers to convey your complete line over motors and drivers that run a belt operated standard conveyor

– AIRTECH CAN HANDLE CONTAINERS EVEN IN CASE OF HEAVY SLOPES

Vetromeccanica has built air conveyance solutions that housed elevators, lowerators, spirals and other stems used in multi level production plants. Their air conveyor is powerful enough to lift filled bottles up and down the heaviest slopes.

 

If conveyance is in your area of interest and you want to learn how this system can be connected to your manufacturing process, give us a call now and we’ll be happy to assist.

1 visitors online now
1 guests, 0 members
Max visitors today: 6 at 12:00 am
This month: 18 at 02-10-2019 08:47 am
This year: 30 at 01-10-2019 02:00 pm
All time: 112 at 02-06-2018 03:16 pm